منابع مشابه
Hyperpolarized xenon for NMR and MRI applications.
Nuclear magnetic resonance (NMR) spectroscopy and imaging (MRI) suffer from intrinsic low sensitivity because even strong external magnetic fields of ~10 T generate only a small detectable net-magnetization of the sample at room temperature (1). Hence, most NMR and MRI applications rely on the detection of molecules at relative high concentration (e.g., water for imaging of biological tissue) o...
متن کاملHyperpolarized NMR Probes for Biological Assays
During the last decade, the development of nuclear spin polarization enhanced (hyperpolarized) molecular probes has opened up new opportunities for studying the inner workings of living cells in real time. The hyperpolarized probes are produced ex situ, introduced into biological systems and detected with high sensitivity and contrast against background signals using high resolution NMR spectro...
متن کاملMolecular Sensing Using Hyperpolarized Xenon NMR Spectroscopy
Although proton-based magnetic resonance imaging (MRI) provides a powerful modality for clinical imaging with excellent spatial resolution, it is not well suited to imaging void spaces (i.e., the lungs), low-abundance molecular markers of disease, or environments where unique proton spin densities are low. To address this limitation, hyperpolarized (hp) xenon-based NMR spectroscopy and MRI have...
متن کاملHyperpolarized Xenon Nuclear Magnetic Resonance (NMR) of Building Stone Materials
We have investigated several building stone materials, including minerals and rocks, using continuous flow hyperpolarized xenon (CF-HP) NMR spectroscopy to probe the surface composition and porosity. Chemical shift and line width values are consistent with petrographic information. Rare upfield shifts were measured and attributed to the presence of transition metal cations on the surface. The e...
متن کاملHyperpolarized 89Y complexes as pH sensitive NMR probes.
Hyperpolarization can increase the sensitivity of NMR/MRI experiments, but the primary limitation is the T(1) decay of magnetization. Due to its long T(1), the hyperpolarized (89)Y nucleus makes an excellent candidate as an in vivo spectroscopy/imaging probe. Here we report the (89)Y chemical shift dependence upon pH for two hyperpolarized (89)Y(III) complexes and demonstrate how such complexes...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Magnetic Resonance in Chemistry
سال: 2018
ISSN: 0749-1581
DOI: 10.1002/mrc.4722